Projects


Unique H3K4 HMT functions in vivo


The impact of histone H3 lysine 4 methylation on gene expression has been challenging to unravel, but these enzymes do so much more….


HMTs as drug targets


MLL1/MLL2 (KMT2A/KMT2B) do very different things…


Pediatric B-ALL: clinical trials and model systems


Testing real-world observations with pediatric-relevant models…


Roles in hematopoietic development


MLL1 plays critical roles in the development of the earliest hematopoietic cells…